Multistate population and whole genome sequence-based strain surveillance of invasive pneumococci recovered in the USA during 2017.

ABSTRACT:

Objectives

We aimed to provide population-based and whole-genome sequence (WGS) -based characterization of invasive pneumococcal disease isolates collected from multistate surveillance in the USA during 2017.

Methods

We obtained short-read WGS from 2881 isolates with associated bioinformatics pipeline strain feature predictions. For quality control, capsular serotypes and antimicrobial MICs were also obtained conventionally from 442 isolates. Annotated WGS were provided (inclusive of serotypes, MICs, multilocus sequence types, pilus type(s)) from 2723 isolates. For 158 isolates with suboptimal WGS, antimicrobial MICs were obtained conventionally.

Results

There were 127 isolates from children <5 years of age and 2754 isolates from those ≥5 years old in 2017. One of 43

SUBMITTER: Varghese J 

PROVIDER: S-EPMC12019393 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature