Identifying purgative targets of sennoside A via <i>in situ</i> biotransformation of prodrug-based probes.

ABSTRACT: •A strategy for in situ metabolically synthesized active drug-based probes was proposed.•The potential purgative targets of SA were successfully hooked and identified.•The work provided a new insight for studying the direct targets of unstable active drugs.

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12019458 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature