Comparative Analysis of Electron Microscopy Techniques for Hydrogel Microarchitecture Characterization: SEM, Cryo-SEM, ESEM, and TEM.

ABSTRACT: Hydrogels have emerged as a versatile class of materials with broad applications in biomedical engineering, drug delivery, and tissue engineering. Understanding their intricate structures and morphologies is crucial for tailoring their properties to meet specific biomedical needs. It has been clearly established that the composition and microarchitecture of the materials play a critical role in essential cellular mechanisms such as mechanosensing, adhesion, and remodeling. This question is essential in tissue engineering, where precisely characterizing the microarchitecture of the materials used to model the cell microenvironment is a critical step to ensure the reproducibility and relevance of reconstructed tissues. In this study, we present a comprehensive comparison of four advanced ele

SUBMITTER: Aigoin J 

PROVIDER: S-EPMC12019757 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature