Efficacy and safety of compound glycyrrhizin in patients with alopecia areata: a systematic review and meta-analysis.

ABSTRACT:

Background

Although compound glycyrrhizin (CG) has been widely used to alopecia areata (AA) in China, its efficacy and safety remain unclear. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of CG for AA.

Materials and methods

Eight literature databases were retrieved from their inceptions to 29 February 2024 to identify the eligible randomized controlled trials comparing CG plus conventional treatments with conventional treatments alone for the treatment of AA. Risk ratio (RR), mean difference and 95% confidence interval (CI) were used to estimate the pooled results. RevMan 5.4 (Cochrane Collaboration, Copenhagen, Denmark) and Stata 12.0 software (StataCorp., College Station, TX) were used for statistical analysis.

Results

A total of

SUBMITTER: Li M 

PROVIDER: S-EPMC12020145 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature