Huddling behavior regulate adaptive thermogenesis in Brandt's voles (Lasiopodomys brandtii).

ABSTRACT:

Background

Brown adipose tissue (BAT) is the main site of non-shivering thermogenesis (NST) in small mammals, playing an important role in maintaining body temperature and energy balance. Huddling is a behavioral strategy for small rodents to save energy and improve the survival under cold environments. However, the way of huddling behavior influence on hypothalamus, which regulate BAT thermogenesis in small mammals is rarely illustrated. We used male Brandt's voles (Lasiopodomys brandtii) to explore the possible regulation mechanisms in BAT thermogenesis by the way of cold acclimation and huddling behavior.

Results

There is a strong relationship between huddling behavior and NST in BAT. The hypothalamus, which is impacted by huddling behavior, influences PPAR signaling path

SUBMITTER: Liu M 

PROVIDER: S-EPMC12020165 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature