Association between the glucose pattern in oral glucose tolerance test and adverse pregnancy outcomes among non-diabetic women.

ABSTRACT:

Background

This study aimed to explore whether the patterns of the oral glucose tolerance test (OGTT) could function as a predictive factor for adverse pregnancy outcomes in pregnant women without gestational diabetes mellitus (GDM).

Methods

A retrospective cohort study was carried out, involving a total of 23,577 pregnant women. The participants were classified into three groups according to the area under the curve (AUC) of the OGTT performed between 24 and 28 weeks of gestation. Based on the tertiles of the AUC-OGTT magnitude, three distinct glucose patterns were identified: small AUC (SA) with an AUC-OGTT ≤ 12.26, medium AUC (MA) with an AUC-OGTT between 12.26 and 13.81, and large AUC (LA) with an AUC-OGTT > 13.81. Logistic regression analysis was utilized to assess the

SUBMITTER: Zhou F 

PROVIDER: S-EPMC12020201 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature