Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study.

ABSTRACT:

Background

This aim of this study was to investigate the prevalence, mortality, and disability-adjusted life year trends of congenital birth defects in children, including the causes of related burdens.

Methods

This cross-sectional study used the 2021 Global Burden of Disease data from 204 countries and regions and included children aged 0-14 (from 1990 to 2021) years with congenital birth defects. The prevalence, all-cause and specific-cause mortality, disability-adjusted life years, and corresponding estimated annual percentage changes (EAPCs) of congenital birth defect burden rates in children were measured. The identified trends were stratified by region, country, sex, and socio-demographic index.

Results

In 2021, approximately 31.64 million children aged 0-14 wor

SUBMITTER: Li Y 

PROVIDER: S-EPMC12020332 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature