Enhancing student understanding of genetic cloning through a 3D-printed active learning activity and flipped classroom curriculum.

ABSTRACT: This classroom curriculum is designed to teach the topic of cloning in both small- and large-enrollment undergraduate general microbiology courses. Students often struggle to grasp and visualize genetic engineering or cloning, in which a piece of DNA is put into a plasmid so that a bacterium may be transformed to produce large quantities of genetic material. Here, we incorporate a hands-on activity featuring 3D-printed models of DNA plasmids and gene inserts within a scaffolded cloning curriculum, designed to enhance student learning and engagement. As students physically manipulate 3D-printed models, with periodic guidance from the instructor, students may refine their scientific thinking about cloning after engaging in lecture-based materials. Uniquely, this activity may also be utilized

SUBMITTER: Popichak KA 

PROVIDER: S-EPMC12020791 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature