Association of Retinal Microvasculature With Myopia Progression in Children: The Hong Kong Children Eye Study.

ABSTRACT:

Purpose

To investigate the associations between optical coherence tomography angiography (OCT-A) metrics and myopia progression in children.

Methods

This prospective, longitudinal cohort study recruited children ages 6 to 8 years for 2- to 6-year follow-ups. OCT-A captured macular images from the superficial capillary plexus (SCP) and deep capillary plexus (DCP). Annual progression of spherical equivalent (SE) and axial length (AL) was calculated as (SE/AL at last visit - SE/AL at baseline)/follow-up duration. Multivariable linear regression analysis evaluated the associations of OCT-A metrics with SE/AL progression. Restricted cubic spline (RCS) analysis evaluated both linear and nonlinear associations. Holm-Bonferroni correction was applied to account for multiple comparis

SUBMITTER: Lin ZX 

PROVIDER: S-EPMC12020977 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature