Allostatic load and its determinants in a German sample-Results from the Carla cohort.

ABSTRACT:

Background

Allostatic load (AL) is a surrogate of the physiological response to stress and reflects the 'wear and tear' on the body. Previous studies indicated that socioeconomic and behavioral determinants influence AL, which in turn is associated with health outcomes. Therefore, AL is increasingly used to operationalize the relationship between social inequality, stress, and health outcomes. This study aimed to investigate associated factors and patterns of AL in the population over a 20-year period using data from the CARLA cohort.

Methods

The analysis included 473 participants from the CARLA study (Cardiovascular Disease, Living and Ageing in Halle), aged 45-80 years at baseline. From recruitment in 2002 in Halle (Saale), three follow-up examinations took place until 202

SUBMITTER: Priedemann E 

PROVIDER: S-EPMC12021213 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature