High-resolution and high-fidelity diffusion tensor imaging of cervical spinal cord using 3D reduced-FOV multiplexed sensitivity encoding (3D-rFOV-MUSE).

ABSTRACT:

Purpose

To develop a 3D isotropic high-resolution and high-fidelity cervical spinal cord DTI technique for addressing the current challenges existing in 2D cervical spinal cord DTI.

Methods

A 3D multi-shot DWI acquisition and reconstruction technique was developed by combining 3D multiplexed sensitivity encoding (3D-MUSE) with two reduced FOV techniques, termed 3D-rFOV-MUSE, to acquire 3D cervical spinal cord DTI data using a sagittal thin slab. A self-referenced 2D ghost correction method and a 2D navigator-based inter-shot phase correction were integrated into the reconstruction framework to simultaneously eliminate Nyquist ghost and aliasing artifacts. Cardiac triggering was used during data acquisition to minimize the influence of cerebrospinal fluid pulsation. In vivo e

SUBMITTER: Yuan C 

PROVIDER: S-EPMC12021329 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature