Molecular analysis of 4/91-like variants of avian infectious bronchitis virus (IBV) obtained after the introduction of a 4/91 live-attenuated vaccine in Costa Rica during 2017.

ABSTRACT: Avian infectious bronchitis virus (IBV) belongs to family Coronaviridae, genus Gammacoronavirus and is one of the most predominant causes of respiratory disease in poultry. Its high mutation rate constantly leads to the emergence of novel variants that complicate disease control. In 2016, a GA13-like IBV outbreak occurred in Costa Rica, prompting the introduction of the 4/91 live-attenuated vaccine. The objective of this research was to perform a molecular characterization of IBV variants circulating in the country six years after the introduction of the 4/91 vaccine. A total of 177 samples from symptomatic birds were analyzed, with 43 testing positive for IBV. Seven complete S1 sequences were obtained and clustered within the GI-13 lineage by phylogenetic analysis. Sequence

SUBMITTER: Vallejo-Arroliga M 

PROVIDER: S-EPMC12021757 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature