Improved in Silico Identification of Protein-Protein Interactions Using Deep Learning Approach.

ABSTRACT: Protein-protein interactions (PPIs) perform significant functions in many biological activities likewise gene regulation, metabolic pathways and signal transduction. The deregulation of PPIs may cause deadly diseases, such as cancer, autoimmune, pernicious anaemia etc. Detecting PPIs can aid in elucidating the cellular process's underlying molecular mechanisms and contribute to facilitating the discovery of new proteins for the development of novel drugs. Although high-throughput wet-lab technologies have been matured to identify large scale PPI identification; however, the traditional experimental methods are costly and slow and resource intensive. To support experimental techniques, numerous computational approaches have been emerged for identifying PPIs solely from protein sequences. Ho

SUBMITTER: Khan I 

PROVIDER: S-EPMC12021994 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature