Predictors of Recovering Full Consciousness: Results From a Prospective Multisite Italian Study.

ABSTRACT:

Background

Improving prognostication in patients with a prolonged disorder of consciousness (pDoC) is among the most challenging issues in neurorehabilitation. The aim of this Italian multisite prospective longitudinal study was to identify valuable predictors of the complete recovery of consciousness (emergence from Minimally Conscious State, eMCS) at 3 months (T1) from the admission in intensive rehabilitation units (IRUs) in pDoC (T0).

Methods

Patients with Unresponsive Wakefulness Syndrome (UWS) or MCS admitted within 3 months of injury to 4 Italian IRUs were included. Demographic, clinical, and neurophysiological data were collected at T0, and a clinical diagnosis of consciousness (UWS, MCS-, MCS+) was established at T0 and T1 using the Coma Recovery Scale-Revised (CRS-

SUBMITTER: Hakiki B 

PROVIDER: S-EPMC12022229 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature