Tissue Engineering and Regenerative Medicine: Perspectives and Challenges.

ABSTRACT: From the pioneering days of cell therapy to the achievement of bioprinting organs, tissue engineering, and regenerative medicine have seen tremendous technological advancements, offering solutions for restoring damaged tissues and organs. However, only a few products and technologies have received United States Food and Drug Administration approval. This review highlights significant progress in cell therapy, extracellular vesicle-based therapy, and tissue engineering. Hematopoietic stem cell transplantation is a powerful tool for treating many diseases, especially hematological malignancies. Mesenchymal stem cells have been extensively studied. The discovery of induced pluripotent stem cells has revolutionized disease modeling and regenerative applications, paving the way for personalized

SUBMITTER: Hoang VT 

PROVIDER: S-EPMC12022429 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature