Real-world efficacy of sublingual immunotherapy with Japanese cedar pollen for cypress pollinosis.

ABSTRACT:

Background

It remains unclear whether allergen immunotherapy with Japanese cedar pollen extract is effective for Japanese cypress pollinosis in real-world settings.

Objective

We sought to investigate the Japan-wide prevalence of cypress pollinosis, the efficacy of cedar sublingual immunotherapy (SLIT) on cypress pollinosis, the role of serum-specific IgE levels in pollinosis, and patients' interest in the development of cypress SLIT.

Methods

A cross-sectional, multicenter study using self-administered questionnaires was conducted in regions of Japan where cedar and cypress pollen dispersals are prevalent. This study included patients aged 5 to 69 years who received cedar SLIT in 2023.

Results

Of 2597 participants analyzed, 84.5% experienced pollinosis symptoms

SUBMITTER: Oka A 

PROVIDER: S-EPMC12022640 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature