Placental and Fetal In Utero Growth Among Fetuses With Congenital Heart Disease.

ABSTRACT:

Importance

At birth, neonates with congenital heart disease (CHD) have smaller placentas, lower birth weight, and smaller head circumferences compared with healthy neonates. The onset of feto-placental growth disturbances, however, is not well known.

Objective

To compare fetal body volumes, assess differences in the fetal to placental volume ratios (placental growth relative to the fetus), and investigate the association between in utero fetal body and total brain volume in fetuses with and without CHD.

Design, setting, and participants

This case-control study enrolled pregnant women with a fetal diagnosis of CHD and those with healthy pregnancies at Children's National Hospital in Washington, DC, from April 2018 to July 2023. Fetal magnetic resonance imaging was obta

SUBMITTER: Jacobwitz M 

PROVIDER: S-EPMC12022807 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature