Pacing therapy for immune checkpoint inhibitors-associated atrioventricular block: a single-center cohort study.

ABSTRACT:

Background

ICI-associated myocarditis is an uncommon yet potentially fatal condition, particularly when concomitant with atrioventricular block (AVB) necessitating pacing. The role of pacing therapy for ICI-associated AVB remains unknown.

Objectives

The aim of this study is to investigate the efficacy and safety of pacing therapy for ICI-associated AVB.

Methods

Patients with ICI-associated myocarditis admitted to Peking Union Medical College Hospital from May 1st 2019 to April 30th 2024 were consecutively screened and the patients with AVB requiring pacing therapy were retrospectively included. Baseline clinical characteristics and initial temporary pacing therapy were evaluated. Follow-up assessments were conducted to evaluate the survival rate and the recovery of at

SUBMITTER: Wang J 

PROVIDER: S-EPMC12023490 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature