Characteristics of upper and lower respiratory tract microbiota after lung transplantation.

ABSTRACT:

Background

The composition and characteristics of airway microbiota offer critical insights for clinical decision-making. Current research on chronic lung diseases shows differences in the composition and characteristics of upper and lower respiratory tract microbiota compared with healthy individuals. However, the temporal changes of these microbial communities in lung transplant recipients remain poorly characterized.

Methods

This is a longitudinal prospective study. Respiratory specimens were collected regularly from lung transplant recipients for testing and analysis. A total of 150 bronchoalveolar lavage fluid (BALF) samples, 150 throat swab samples, 51 sputum samples, and 36 lung tissue samples were collected from the recipients, at 7 days, 14 days, 1 month, 2 months,

SUBMITTER: Cai Y 

PROVIDER: S-EPMC12023598 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature