Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions for 2022-2040.

ABSTRACT:

Objectives

Congenital birth defects (CBDs) rank among the top five causes of death in children under the age of five. Despite their significant impact, studies on the burden of CBDs in G20 countries remain limited. This study sought to examine the temporal trends in the disease burden and mortality rates of CBDs across G20 countries from 1990 to 2021, identify potential risk factors contributing to these trends, and project the disease burden and mortality rates for the period 2022-2040.

Method

Data for this study were obtained from the Global Burden of Disease (GBD) 2021 and GBD 2019 databases. We analyzed trends in disability-adjusted life years (DALYs) and mortality rates for CBDs in G20 countries using absolute numbers, all-age rates, age-standardized rates (ASR), annual

SUBMITTER: Li X 

PROVIDER: S-EPMC12023674 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature