Community surveillance after detection of poliovirus in the environment in London, United Kingdom, October 2022 to April 2023.

ABSTRACT: BackgroundVaccine-derived polioviruses (VDPVs) continue to circulate internationally, causing sporadic cases and outbreaks of paralytic polio in countries certified as polio-free. In 2022, sustained detection of type 2 VDPVs was reported in environmental surveillance samples collected from London. Genetic mutations indicative of loss of attenuation of virulence were observed, consistent with community transmission events over several months.AimWe aimed to determine the extent of geographical spread of transmission in an area of environmental poliovirus detection.MethodsWe implemented an opportunistic, cross-sectional survey in areas where environmental surveillance indicated sustained VDPV transmission between October 2022 and April 2023. Residual stool samples taken from children < 16 yea

SUBMITTER: Rowland T 

PROVIDER: S-EPMC12023727 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature