The impact of ascending aorta dilatation on transcatheter aortic valve implantation outcomes.

ABSTRACT: The impact of ascending aorta dilatation (AAD) on transcatheter aortic valve implantation (TAVI) outcomes, compared to non-AAD, remains unclear. This meta-analysis aims to compare the outcomes of TAVI between patients with and without AAD. We systematically searched PubMed, ScienceDirect, Web of Science, Springer, Cochrane, and Clinicaltrials.gov. for articles up to 25 March 2024 (PROSPERO ID CRD42024526311). A total of 204,078 patients from ten studies were included. Paravalvular regurgitation (RR 1.56 95 %CI: 1.32-1.84, p < 0.00001, I² = 0 %) and aortic dissection (RR 3.55 95 %CI: 1.79-7.06, p = 0.0003, I² = 40 %) were more common in AAD group. However, there were no differences in peri-procedural (RR 1.09, 95 %CI: 0.83-1.42, p = 0.53, I² = 

SUBMITTER: Saputra PBT 

PROVIDER: S-EPMC12023879 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature