CT-Based Lung Size Matching in Delayed Chest Closure for Systemic Sclerosis Lung Transplantation.

ABSTRACT:

Purpose

Delayed chest closure (DCC) during lung transplantation (LTx) is a controversial surgical approach that lacks research in systemic sclerosis (SSc) patients. We investigated outcomes, clinical risk factors, and CT-based lung size-matching parameters associated with DCC in SSc recipients.

Methods

This retrospective study included 92 SSc recipients (age 51 years ± 10, 56/92 (61.0%) females) who underwent bilateral LTx between 2007 and 2020. Of the recipients, 34.8% (32/92) underwent DCC. Recipient lung and chest cavity volumes were automatically computed from CT imaging using deep learning algorithms. Survival between groups was compared using Kaplan-Meier analysis. Multivariate logistic regression was used to identify risk factors and predict DCC occurrence using preop

SUBMITTER: Singh J 

PROVIDER: S-EPMC12023910 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature