Effects of Ammonia Stress on the Antioxidant, Ferroptosis, and Immune Response in the Liver of Golden Pompano <i>Trachinotus ovatus</i>.

ABSTRACT: Ammonia is the main harmful environmental substance affecting fish culture. The liver is the immune and metabolic organ of fish, and its physiological homeostasis will affect the health of the organism. In this study, healthy golden pompano Trachinotus ovatus juveniles were exposed to 5 mg/L (A5) and 10 mg/L (A10) ammonia-N stress for 7 days and then the variation characteristics of the physiological homeostasis of the liver were analyzed at multiple biological levels. After ammonia stress, the liver showed obvious morphological changes and stress responses. Specifically, the oxidative stress indexes, such as the activities of the anti-superoxide anion generation capacity (ASC) and superoxide dismutase (SOD), were elevated in the A5 and A10 groups, while the glutathione peroxidase (

SUBMITTER: Duan Y 

PROVIDER: S-EPMC12024250 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature