Detection of <i>Cereibacter azotoformans</i>-YS02 as a Novel Source of Coenzyme Q10 and Its Metabolic Analysis.

ABSTRACT: Coenzyme Q10 (CoQ10), a high-value-added nutraceutical antioxidant, exhibits an excellent ability to prevent cardiovascular disease. Here, a novel Cereibacter azotoformans strain, designated YS02, was isolated for its ability to produce CoQ10 and genetically characterized by whole genome sequencing (WGS). The CoQ10 biosynthesis and metabolism differences of YS02 under various culture conditions were also systematically investigated. Phylogenetic analysis based on 16 S rRNA genes, along with taxonomic verification using average nucleotide identity (ANI) analysis, confirmed its classification as C. azotoformans. Enzymatic genes dxs, dxr, idi, ubiA, and ubiG were annotated in YS02, which are critical genetic hallmarks for CoQ10 biosynthesis. Under aer

SUBMITTER: Song M 

PROVIDER: S-EPMC12024278 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature