MRI Delta Radiomics to Track Early Changes in Tumor Following Radiation: Application in Glioblastoma Mouse Model.

ABSTRACT: Background/Objectives: Glioblastoma (GBM) is an aggressive and lethal primary brain tumor with a poor prognosis, with a 5-year survival rate of approximately 5%. Despite advances in oncologic treatments, including surgery, radiotherapy, and chemotherapy, survival outcomes have remained stagnant, largely due to the failure of conventional therapies to address the tumor's inherent heterogeneity. Radiomics, a rapidly emerging field, provides an opportunity to extract features from MRI scans, offering new insights into tumor biology and treatment response. This study evaluates the potential of delta radiomics, the study of changes in radiomic features over time in response to treatment or disease progression, exploring the potential of delta radiomics to track temporal radiation changes

SUBMITTER: Alshuhri MS 

PROVIDER: S-EPMC12024708 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature