Molecular Characterization and Nutritional Regulation of Two Fatty Acid Elongase (<i>elovl8</i>) Genes in Chinese Perch (<i>Siniperca chuatsi</i>).

ABSTRACT: Proteins for elongation of very long-chain fatty acids (ELOVLs) are critical for the synthesis of long-chain polyunsaturated fatty acids (LC-PUFAs), and they are one group of the rate-limiting enzymes responsible for the initial condensation reaction within the fatty acid elongation. Elovl8 is a newly identified member of the ELOVL protein family, and its evolutionary and functional characterizations are still rarely reported. Here, we identified two elovl8 paralogues (named Scelovl8 and Scelovl8b) from Chinese perch (Siniperca chuatsi), and then their molecular and evolutionary characteristics, as well as potential roles involved in LC-PUFA biosynthesis, were examined. The ORFs of both Scelovl8a and Scelovl8b genes were 810 bp and 789 bp in length

SUBMITTER: He Y 

PROVIDER: S-EPMC12025145 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature