Etiologies of Multidrug-Resistant Epilepsy in Latin America: A Comprehensive Review of Structural, Genetic, Metabolic, Inflammatory, and Infectious Origins: A Systematic Review.

ABSTRACT: Epilepsy is a prevalent neurological disorder that affects millions worldwide, with a significant portion of individuals experiencing drug-resistant forms of the condition. In Latin America, the challenge of identifying the underlying causes of multidrug-resistant epilepsy (MDRE) is particularly pressing. (1) Background: This systematic review aims to highlight the critical importance of understanding the etiology of MDRE in Latin America. (2) Methods: A systematic review of Medline (PubMed), Scopus, and Web of Science was conducted following the PRISMA methodology; articles were selected if they included information on the etiology of MDRE in Latin-American participants, and the NHLBI tool was used to assess bias. (3) Results: A total of 37 published articles were finally included in the

SUBMITTER: Hinojosa-Figueroa MS 

PROVIDER: S-EPMC12025188 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature