White-Matter Connectivity and General Movements in Infants with Perinatal Brain Injury.

ABSTRACT:

Background/objectives

Cerebral palsy (CP), often caused by early brain injury such as perinatal stroke or hemorrhage, is the most common lifelong motor disability. Early identification of at-risk infants and timely access to rehabilitation interventions are essential for improving long-term outcomes. The General Movements Assessment (GMA), performed in the first months of life, has high sensitivity and specificity to predict CP; however, the neurological correlates of general movements remain unclear. This analysis aimed to investigate the relationship between white matter integrity and general movements in infants with perinatal brain injury using advanced neuroimaging techniques.

Methods

Diffusion-weighted MRI data were analyzed in 17 infants, 12 with perinatal brain injur

SUBMITTER: Sutter EN 

PROVIDER: S-EPMC12025426 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature