Cost-Effectiveness of Screening and Treating Chronic Hepatitis C Virus Infection in Zimbabwe.

ABSTRACT:

Background

The aim of this study was to assess the cost effectiveness of a screening and treatment intervention approach for chronic HCV infection in Zimbabwe.

Methods

Using a decision tree and a validated Markov model, we estimated the lifetime costs and health effects of screening for and treating HCV infections from a healthcare perspective. We evaluated three screening strategies, namely the following: i. no screening; ii. screening among the general population; and iii. screening among high-risk groups. Incremental cost effectiveness ratios were calculated for the strategies that were not dominated. We used deterministic and probabilistic sensitivity analyses to explore the impacts of parameter uncertainty on cost effectiveness outcomes.

Results

The strategy of s

SUBMITTER: Dzingirai B 

PROVIDER: S-EPMC12026964 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature