The Burden of Illness of Treatment-Induced Vasomotor Symptoms in Individuals with Breast Cancer: A Systematic Literature Review.

ABSTRACT: Objective: This systematic literature review (SLR) evaluates the global burden of treatment-induced vasomotor symptoms (VMSs) in individuals with breast cancer receiving tamoxifen or aromatase inhibitors (AIs). Methods: Embase and PubMed were searched for observational and interventional studies published between January 2010 and January 2023 reporting on adults who experienced moderate to severe VMSs after tamoxifen or AI treatment for breast cancer. Epidemiological, clinical, humanistic, economic, and treatment pattern data were extracted where available. Results: Of 694 unique publications identified, 37 independent studies (22 observational and 15 interventional) were included. The prevalence or incidence of treatment-induced VMSs was reported in 17 studies. The pr

SUBMITTER: Morga A 

PROVIDER: S-EPMC12027725 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature