Migraine and Tension-Type Headache Are Associated with Multiple Sclerosis: A Case-Control Study.

ABSTRACT: Background/Objectives: Over the past few decades, there has been increased scientific interest in the prevalence of headache disorders among people with MS (pwMS). Although the latest data suggest an association between migraine and multiple sclerosis, studies have been providing inconsistent results largely due to methodological differences, including small sample sizes, lack of control groups, absence of structured headache diaries, and variability in diagnostic criteria. This study aims to address the question of whether pwMS have a higher prevalence of primary headache disorders than healthy controls (HCs) and whether MS is associated with an increased risk of headaches. Methods: In this cross-sectional, case-control study, consecutive pwMS from Eginition University Hospi

SUBMITTER: Gklinos P 

PROVIDER: S-EPMC12027967 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature