The Frequency and Spread of a GABA-Gated Chloride Channel Target-Site Mutation and Its Impact on the Efficacy of Ethiprole Against Neotropical Brown Stink Bug, <i>Euschistus heros</i> (Hemiptera: Pentatomidae).

ABSTRACT: The Neotropical brown stink bug (NBSB), Euschistus heros, is the most prevalent sucking soybean pest in Brazil, and control of it largely relies on the application of synthetic insecticides such as ethiprole, a phenylpyrazole insecticide targeting GABA-gated chloride channels encoded by the Rdl (resistant to dieldrin) gene. This study monitored 41 NBSB populations collected between 2021 and 2024 and revealed, for the first time, the presence of a mutation, A301S, in NBSB RDL receptors commonly known to confer target-site resistance to channel blockers such as phenylpyrazoles. Laboratory contact bioassays with ethiprole at 150 g a.i./ha (ethiprole label dose) revealed that most populations were quite susceptible, despite rather high resistance allele frequencies in some popula

SUBMITTER: Cuenca ACP 

PROVIDER: S-EPMC12028171 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature