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Obesity Paradox in Takotsubo Syndrome Among Septic ICU Patients: A Retrospective Cohort Study.


ABSTRACT: Background: Takotsubo Syndrome (TTS) is a transient left ventricular systolic dysfunction typically characterized by anteroseptal-apical dyskinetic ballooning of the left ventricle with a hyperkinetic base, without significant obstructive coronary artery disease. The interplay between systemic inflammation and hemodynamic stress in sepsis exacerbates susceptibility to TTS. We aim to investigate the characteristics and factors associated with TTS in critically ill patients with sepsis admitted to the intensive care unit. Methods: A retrospective cohort study was conducted on 361 patients admitted to the medical ICU at a tertiary care hospital in New York City. All patients underwent transthoracic echocardiography (TTE) within 72 h of sepsis diagnosis. Patients were divided int

SUBMITTER: Yakkali S 

PROVIDER: S-EPMC12028263 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature