Thrombectomy for Ischemic Stroke Beyond 24 Hours: A Meta-Analysis.

ABSTRACT:

Background

The DEFUSE-3 and DAWN studies established the benefits of endovascular therapy for patients with stroke with large vessel occlusion in a 6-24 h time window. However, the effectiveness of endovascular therapy performed beyond 24 h remains uncertain. The purpose of this meta-analysis is to evaluate the difference in prognosis between thrombectomies performed beyond 24 h and within 24 h from ischemic stroke onset.

Methods

A systematic review was conducted using the PubMed, Cochrane, and Embase databases from database inception until 1 February 2024. Odds ratios with 95% confidence intervals were calculated.

Results

This study included seven cohort articles involving 6137 participants who received endovascular therapy, with 395 patients in the beyond 24 h group

SUBMITTER: Chiu HT 

PROVIDER: S-EPMC12028478 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature