Optimization of Nanoencapsulation of <i>Codium tomentosum</i> Extract and Its Potential Application in Yogurt Fortification.

ABSTRACT: Marine macroalgae are excellent sources of bioactive compounds recognized by their pharmaceutical and biomedical potential. A subcritical water extraction (SWE) was applied to the macroalga Codium tomentosum, and the extract was used to prepare phytosomes. A Box-Behnken design was applied to optimize the entrapment efficiency. These phytosomes were further modified with DSPE-PEG (2000)-maleimide and apolipoprotein E and characterized by dynamic light scattering, UV spectrophotometry, octanol/water partition coefficient, differential scanning calorimetry, and Fourier transform infrared spectroscopy. As proof of concept, prototypes of functional food tailored to the elderly were produced. Yogurts were fortified with seaweed extract or phytosomes, and physicochemical properties and pro

SUBMITTER: Costa M 

PROVIDER: S-EPMC12028962 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature