The Subgingival Microbial Composition in Health and Periodontitis with Different Probing Depths.

ABSTRACT: The differences in microbiota between periodontitis and health have been extensively studied; however, knowledge about how the microbiota shifts from shallow to deep periodontal pockets remains limited despite its clinical importance in disease progres-sion and management. Patients diagnosed with stage III periodontitis commonly pre-sent varied probing depths (PD) within the same oral cavity, reflecting localized disease severity. This study aims to analyze the microbiome of subgingival plaques at various PDs in periodontitis patients. Subgingival plaques were collected from sixteen healthy subjects (health group) and periodontal pockets of sixteen stage III periodontitis pa-tients (PD 0-3 mm, PD 4-5 mm and PD 6-9 mm groups). A total of 64 subgingival plaque samples underwent 16S rRNA gene

SUBMITTER: Wang J 

PROVIDER: S-EPMC12029188 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature