In Vivo Study on the Salivary Kinetics of Two Probiotic Strains Delivered via Chewing Gum.

ABSTRACT: Probiotics are increasingly used to promote oral health, with Lacticaseibacillus rhamnosus demonstrating proven effectiveness. Additionally, Heyndrickxia coagulans shows promising potential in this field. Chewing gum has recently been proposed as an innovative delivery method for probiotics. This study aimed to evaluate the kinetics in saliva of Heyndrickxia coagulans SNZ1969^® and Lacticaseibacillus rhamnosus GG in microencapsulated and non-microencapsulated forms (LGG^®) following their administration via sugar-free chewing gums. A randomized cross-over trial was conducted involving 10 volunteers. Participants chewed gums containing one of the probiotic strains for 10 min. Saliva samples were collected at baseline (T₀) and six su

SUBMITTER: Cirio S 

PROVIDER: S-EPMC12029345 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature