Development and Validation of an HPLC-PDA Method for Quality Control of Jwagwieum, an Herbal Medicine Prescription: Simultaneous Analysis of Nine Marker Compounds.

ABSTRACT: Background/Objectives: Jwagwieum (or Joa-Gui Em; JGE) consists of six herbal medicines, Rehmannia glutinosa (Gaertn.) DC., Dioscorea japonica Thunb., Lycium chinense Mill., Cornus officinalis Siebold & Zucc., Poria cocos Wolf, and Glycyrrhiza uralensis Fisch., and has been widely used to treat kidney-yin deficiency syndrome. In the present study, a high-performance liquid chromatography with photodiode array detector (HPLC-PDA) method for the simultaneous quantification of the nine components, i.e., gallic acid, 5-(hydroxymethyl)furfural, morroniside, loganin, liquiritin apioside, liquiritin, ononin, glycyrrhizin, and allantoin, was developed. Methods: The developed HPLC-PDA assay for quality control of JGE was validated with respect

SUBMITTER: Seo CS 

PROVIDER: S-EPMC12030021 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature