New Cannabinoids and Chlorin-Type Metabolites from the Flowers of <i>Cannabis sativa</i> L.: A Study on Their Neuroblastoma Activity.

ABSTRACT: Background/Objectives: Cannabis sativa has been utilized for medical purposes for thousands of years. It continues to be recognized as a plant with an extensive variety of medicinal and nutraceutical uses today. In this study, a chemical investigation of the flowers of C. sativa isolated by using a variety of chromatographic techniques led to the isolation of eleven compounds. These purified compounds were evaluated for antitumor activity against SK-N-SH neuroblastoma cells. Methods: The compounds were isolated by using chromatographic techniques. Their structures were identified by the examination of spectroscopic methods, including 1D (¹H, ¹³C, and DEPT) and 2D (COSY, HSQC, HMBC, and NOESY) nuclear magnetic resonance (NMR) spectra and mas

SUBMITTER: Nguyen TQ 

PROVIDER: S-EPMC12030031 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature