Hybrid <i>Bis</i>-(Imidazole/Benzimidazole)-Pyridine Derivatives with Antifungal Activity of Potential Interest in Medicine and Agriculture via Improved Efficiency Methods.

ABSTRACT: Background/Objectives: Nowadays fungal infections are rising serious threats for the human health system and agriculture, mostly because of antifungal resistance, emergence of new fungal pathogens and adverse effects, pressing the scientific world for exploration of new antifungal compounds. Therefore, the aim of this work was to synthesize and to study antifungal activity against human and plant fungi of a new class of hybrid bis-(imidazole/benzimidazole)-pyridine salt derivatives. Methods: The synthesis of the hybrid derivatives was performed using both conventional thermal heating and ultrasound irradiation methods. Results: The use of ultrasound irradiation has the advantages of a dramatic decrease in reaction time and, consequently, a notable acceleration i

SUBMITTER: Balaes T 

PROVIDER: S-EPMC12030448 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature