Integrating Complex Permittivity Measurements with Histological Analysis for Advanced Tissue Characterization.

ABSTRACT: We developed a measurement setup and protocol reliably relating complex permittivity measurements with tissue characterization and specific histological features. We measured 148 fresh human tissue samples across 14 tissue types at 51 frequencies ranging from 200 MHz to 20 GHz, using an open-ended coaxial slim probe. Tissue samples were collected using a punch biopsy, ensuring that the sampled area encompassed the region where complex permittivity measurements were performed. This approach minimized experimental uncertainty related to potential position-dependent variations in permittivity. Once measured, the samples were then formalin-fixed and paraffin-embedded (FFPE) to obtain histological slides for microscopic analysis of tissue features. We observed that complex permittivity values a

SUBMITTER: Lopez-Prades S 

PROVIDER: S-EPMC12030891 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature