Chronic Hepatitis B in the Transplant Setting: A 30-Year Experience in a Single Tertiary Italian Center.

ABSTRACT:

Background

Hepatitis B virus (HBV) remains a leading etiology for liver transplantation (LT). In a large cohort of HBsAg-positive patients, this study evaluates long-term patient and graft survival after LT over the past 30 years while analyzing trends and outcomes following waiting list (WL) inclusion over the last 15 years.

Methods

HBsAg-positive patients who underwent transplantation between 1991 and 2020 and were waitlisted from 2006 to 2020 at Padua Hospital were included in the analysis. Patients were stratified according to hepatitis delta virus (HDV) coinfection, transplant indication (decompensated cirrhosis vs. hepatocellular carcinoma (HCC)), and WL inclusion period.

Results

Among 321 HBsAg-positive LT recipients (31.5% HDV-coinfected, 46.4% HCC), 1-year an

SUBMITTER: Russo FP 

PROVIDER: S-EPMC12030929 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature