Copper Nanoclusters Anchored on Crumpled N-Doped MXene for Ultra-Sensitive Electrochemical Sensing.

ABSTRACT: Simultaneous detection of dopamine (DA) and uric acid (UA) is essential for diagnosing neurological and metabolic diseases but hindered by overlapping electrochemical signals. We present an ultrasensitive electrochemical sensor using copper nanoclusters anchored on nitrogen-doped crumpled Ti₃C₂T_x MXene (Cu-N/Ti₃C₂T_x). The engineered 3D crumpled architecture prevents MXene restacking, exposes active sites, and enhances ion transport, while Cu nanoclusters boost electrocatalytic activity via accelerated electron transfer. Structural analyses confirm uniform Cu dispersion (3.0 wt%), Ti-N bonding, and strain-induced wrinkles, synergistically improving conductivity. The sensor achieves exceptional sensitivity (1958.3 and 1152.7 μ

SUBMITTER: Yang H 

PROVIDER: S-EPMC12031129 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature