Meta-Analysis of Dietary Interventions for Enteric Methane Mitigation in Ruminants Through Methodological Advancements and Implementation Pathways.

ABSTRACT: This meta-analysis systematically evaluates the efficacy of dietary interventions for mitigating enteric methane production in ruminants through the application of advanced statistical methodologies. A comprehensive dataset comprising 119 peer-reviewed publications (2000-2024) was analyzed using robust variance estimation, multilevel modeling, and network meta-analysis to quantify intervention efficacy and identify moderating factors while properly accounting for within-study dependencies. The results demonstrate a clear efficacy hierarchy of macroalgae (51.0% reduction [95% CI: 37.0-63.0%]), 3-nitrooxypropanol (3-NOP; 30.6% [95% CI: 22.0-45.0%]), nitrate (16.0% [95% CI: 6.0-26.0%]), oils (14.7% [95% CI: 5.0-24.0%]), and phytochemicals (13.5% [95% CI: 4.0-22.0%]). The meta-regression analy

SUBMITTER: Purba RAP 

PROVIDER: S-EPMC12031153 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature