Non-Invasive Real-Time Monitoring of Bacterial Activity by Non-Contact Impedance Spectroscopy for Off-the-Shelf Labware.

ABSTRACT: Monitoring bacterial activity is essential for numerous scientific and industrial applications. However, current benchmark measurements, i.e., optical density (OD), exhibit a limited dynamic range and require transparent or translucent media. Conventional impedance spectroscopy involves direct electrode contact with the bacterial medium or biofilm, potentially perturbing the sample environment and compromising measurement fidelity. Moreover, many real-time methods rely on costly, specialized labware that limits scalability and versatility. Here, we introduce a non-contact impedance spectroscopy (NCIS) technique with customizable electrodes for off-the-shelf labware and show that the data collected from a KCl solution series agree well with the simplest electrolytic conductivity cell model

SUBMITTER: Thirstrup C 

PROVIDER: S-EPMC12031269 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature