Aflatoxin M1 Determination in Whole Milk with Immersible Silicon Photonic Immunosensor.

ABSTRACT: Aflatoxin M1 (AFM1) appears in the milk of animals that have consumed feed contaminated with aflatoxin B1. AFM1 presence in milk is regulated by the European Commission, which has set the maximum allowable limits for adult and infant consumption to 50 and 25 pg/mL, respectively. Here, a rapid and sensitive method for detecting AFM1 in milk based on an immersible silicon photonic chip is presented. The chip features two U-shaped silicon nitride waveguides formed as Mach-Zehnder interferometers. One interferometer is functionalized with AFM1-bovine serum albumin conjugate and the other with BSA to serve as a blank. The chip is connected to a broad-band white LED and a spectrophotometer by a bifurcated optical fiber and an assay is performed by immersing the chip in a mixture of milk with the

SUBMITTER: Kourti D 

PROVIDER: S-EPMC12031367 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature