Phylogeographic Patterns and Genetic Diversity of <i>Anopheles stephensi</i>: Implications for Global Malaria Transmission.

ABSTRACT: Background: Anopheles stephensi, a primary malaria vector in South Asia, is expanding its geographic range, raising concerns about increased malaria transmission. However, critical aspects of its genetic diversity, population structure, and evolutionary dynamics remain poorly understood in Khyber Pakhtunkhwa (KP), Pakistan, an endemic malaria region where An. stephensi is adapting to urban settings, posing challenges for the development of targeted vector control strategies. This study addresses this gap by analyzing COI, COII (cytochrome oxidase subunit I and II), and ITS2 (internal transcribed spacer 2) sequences from An. stephensi populations in KP and comparing them with global isolates. Additionally, egg morphology analysis was conducted to identify the bio

SUBMITTER: Khan J 

PROVIDER: S-EPMC12031451 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature