Relationship between intraoperative blood pressure variability and postoperative acute kidney injury in pediatric cardiac surgery.

ABSTRACT:

Background

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a notably common complication in pediatrics, with an incidence rate ranging from 15 to 64%. This rate is significantly higher than that observed in adults. Currently, there is a lack of substantial evidence regarding the association between intraoperative blood pressure variability (BPV) during cardiac surgery with cardiopulmonary bypass (CPB) and the development of AKI in pediatric patients.

Methods

This retrospective observational study encompassed children aged 0-7 years undergoing cardiac surgery with CPB. Intraoperative BPV was calculated using coefficients of variation (CVs) and the area under the curve (AUC). Univariate and multivariate analyses were employed to identify risk factors associated wit

SUBMITTER: Xiao R 

PROVIDER: S-EPMC12031837 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature