National Trends and Outcomes of Combined Lung-Liver Transplantation: An Analysis of the UNOS Registry.

ABSTRACT:

Purpose

Combined lung-liver transplant (CLLT) is a complex yet life-saving procedure for patients with simultaneous end-stage lung and liver disease. Given the geographical allocation change to the lung allocation score (LAS) in 2017 and the recent SARS-CoV-2 outbreak in 2019, we aim to provide an updated analysis of the patient selection and outcomes of CLLTs.

Methods

The UNOS registry was used to identify all patients who underwent CLLT between January 2014 and June 2023. To account for the changes made to LAS in 2017, baseline characteristics and outcomes were compared between era 1 (before 2017) and era 2 (after 2017). Risk factors for mortality were analyzed using the Cox regression hazard models. Recipient survival of up to 3 years was analyzed using the Kaplan-Meier m

SUBMITTER: Bao BJ 

PROVIDER: S-EPMC12031901 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature